产品名称
MT-ND1 Rabbit Polyclonal Antibody (N-term)
别名
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1, MT-ND1, MTND1, NADH1, ND1
存储缓冲液
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) New type preservative N. This antibody is purified through a protein A column, followed by peptide affinity purification.
Human Swissprot No.
P03886
特异性
This MT-ND1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 34-68 amino acids from the N-terminal region of human MT-ND1.
运输及保存条件
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
背景介绍
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
细胞定位
Mitochondrion inner membrane {ECO:0000250|UniProtKB:P03887}; Multi-pass membrane protein
功能
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (PubMed:
1959619). Essential for the catalytic activity and assembly of complex I (PubMed:
26929434, PubMed:
1959619).