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TIMM50 Rabbit Polyclonal Antibody (N-term)

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产品基本信息

产品货号
BD-PB4846
产品名称
TIMM50 Rabbit Polyclonal Antibody (N-term)
别名
Mitochondrial import inner membrane translocase subunit TIM50, TIMM50, TIM50
类别
常规抗体
推荐应用
WB
反应种属
Human
存储缓冲液
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) New type preservative N. This antibody is purified through a protein A column, followed by peptide affinity purification.
Human Swissprot No.
Q3ZCQ8
特异性
This TIMM50 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 25-56 amino acids from the N-terminal region of human TIMM50.
稀释度
WB~~1:1000
预测分子量
40kDa
运输及保存条件
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
宿主
Rabbit
同种型
Rabbit IgG
背景介绍
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo. Isoform 2 may participate in the release of snRNPs and SMN from the Cajal body.
组织表达
Widely expressed. Expressed at higher level in brain, kidney and liver (at protein level)
细胞定位
Mitochondrion inner membrane; Single-pass membrane protein
功能
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo.
期货
现货

Western blot analysis of lysate from human heart tissue lysate, using TIMM50 Antibody (N-term)at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.

Western blot analysis of lysates from Hela, HepG2, SH-SY5Y cell line (from left to right), using TIMM50 Antibody (N-term)at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.

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