产品名称
GSN Rabbit Polyclonal Antibody (N-term)
别名
Gelsolin, AGEL, Actin-depolymerizing factor, ADF, Brevin, GSN
存储缓冲液
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) New type preservative N. This antibody is purified through a protein A column, followed by peptide affinity purification.
Human Swissprot No.
P06396
特异性
This GSN antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 36-70 amino acids from the N-terminal region of human GSN.
运输及保存条件
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
背景介绍
Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.
组织表达
Phagocytic cells, platelets, fibroblasts, nonmuscle cells, smooth and skeletal muscle cells
细胞定位
[Isoform 2]: Cytoplasm, cytoskeleton.
功能
Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.
