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SDHA Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号
BD-PB4717
产品名称
SDHA Rabbit Polyclonal Antibody (C-term)
别名
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial, Flavoprotein subunit of complex II, Fp, SDHA, SDH2, SDHF
类别
常规抗体
推荐应用
WB
反应种属
Human, Rat, Mouse
存储缓冲液
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) New type preservative N. This antibody is purified through a protein A column, followed by peptide affinity purification.
Human Gene ID
NP_004159.2
Human Swissprot No.
P31040
特异性
This SDHA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 577-605 amino acids from the C-terminal region of human SDHA.
稀释度
IHC-P~~1:100~500;WB~~1:1000
预测分子量
73kDa
运输及保存条件
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
宿主
Rabbit
同种型
Rabbit IgG
背景介绍
Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Can act as a tumor suppressor.
细胞定位
Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q0QF01}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q0QF01}; Matrix side {ECO:0000250|UniProtKB:Q0QF01}
功能
Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (PubMed:24781757). Can act as a tumor suppressor (PubMed:20484225).
期货
现货

Immunohistochemical analysis of paraffin-embedded H. skeletal muscle section using SDHA Antibody (C-term). BD-PB4717 was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.

SDHA Antibody (C-term) western blot analysis in Hela and mouse C2C12 cell line lysates (35ug/lane).This demonstrates the DHSA antibody detected the DHSA protein (arrow).

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