BD-PB4699

ERCC1 (19J9) Mouse Monoclonal Antibody (C-term)

DNA excision repair protein ERCC-1, ERCC1

常规抗体

WB

Human, Mouse

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) New type preservative N. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.

NP_001159521.1;NP_001974.1;NP_973730.1

P07992

This ERCC1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 268-297 amino acids from the C-terminal region of human ERCC1.

WB~~1:2000

33kDa

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Mouse

IgM,k

Structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair.

[Isoform 1]: Nucleus [Isoform 3]: Nucleus

[Isoform 1]: Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4.

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