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FCGR2A Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号
BD-PB4661
产品名称
FCGR2A Rabbit Polyclonal Antibody (C-term)
别名
Low affinity immunoglobulin gamma Fc region receptor II-a, IgG Fc receptor II-a, CDw32, Fc-gamma RII-a, Fc-gamma-RIIa, FcRII-a, CD32, FCGR2A, CD32, FCG2, FCGR2A1, IGFR2
类别
常规抗体
推荐应用
WB
反应种属
Human
存储缓冲液
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) New type preservative N. This antibody is purified through a protein A column, followed by peptide affinity purification.
Human Gene ID
NP_001129691.1;NP_067674.2
Human Swissprot No.
P12318
特异性
This FCGR2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 255-282 amino acids from the C-terminal region of human FCGR2A.
稀释度
WB~~1:1000;FC~~1:10~50
预测分子量
35kDa
运输及保存条件
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
宿主
Rabbit
同种型
Rabbit IgG
背景介绍
FCGR2A is one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants.
组织表达
Found on monocytes, neutrophils and eosinophil platelets
细胞定位
Cell membrane; Single-pass type I membrane protein
功能
Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.
期货
现货

Western blot analysis of lysate from Jurkat cell line,using FCGR2A Antibody (C-term)at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug per lane.

FCGR2A Antibody (C-term) flow cytometric analysis of MDA-MB435 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

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