产品名称
UBE2Z Rabbit Polyclonal Antibody
蛋白名称
Ubiquitin-conjugating enzyme E2 Z (EC 6.3.2.19) (Uba6-specific E2 conjugating enzyme 1) (Use1) (Ubiquitin carrier protein Z) (Ubiquitin-protein ligase Z)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9H832
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9H832/entry
Mouse Swissprot No.
Q3UE37
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q3UE37
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q3B7D1
免疫原
Synthesized peptide derived from part region of human protein
特异性
UBE2Z Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes an enzyme which ubiquitinates proteins which participate in signaling pathways and apoptosis. [provided by RefSeq, Feb 2012],
组织表达
Widely expressed. Highly in placenta, pancreas, spleen and testis.
细胞定位
Cytoplasm . Nucleus .
信号通路
Ubiquitin mediated proteolysis;
功能
catalytic activity:ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.,function:Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity). Specific substrate for UBE1L2, not charged with ubiquitin by UBE1. May be involved in apoptosis regulation.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the ubiquitin-conjugating enzyme family.,tissue specificity:Widely expressed. Highly in placenta, pancreas, spleen and testis.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.