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SERPINF1 Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号
BD-PB4594
产品名称
SERPINF1 Rabbit Polyclonal Antibody (Center)
别名
Pigment epithelium-derived factor, PEDF, Cell proliferation-inducing gene 35 protein, EPC-1, Serpin F1, SERPINF1, PEDF
类别
常规抗体
推荐应用
WB
反应种属
Human
存储缓冲液
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) New type preservative N. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Human Gene ID
NP_002606.3
Human Swissprot No.
P36955
特异性
This SERPINF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 279-306 amino acids from the Central region of human SERPINF1.
稀释度
WB~~1:1000;IHC-P~~1:100~500;FC~~1:10~50
预测分子量
46kDa
运输及保存条件
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
宿主
Rabbit
同种型
Rabbit IgG
背景介绍
SERPINF1 is a member of the serpin family. Serpins are a group of serine protease inhibitors, some of which have also been reported to exhibit neurotrophic activity.
组织表达
Retinal pigment epithelial cells and blood plasma.
细胞定位
Secreted. Melanosome. Note=Enriched in stage I melanosomes
功能
Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
期货
现货

SERPINF1 Antibody (Center) western blot analysis in human blood plasma tissue lysates (35ug/lane).This demonstrates the SERPINF1 antibody detected the SERPINF1 protein (arrow).

Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with SERPINF1 Antibody (Center) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

SERPINF1 Antibody (Center) flow cytometry analysis of K562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

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