产品名称
UBE2Z Rabbit Polyclonal Antibody
蛋白名称
Ubiquitin-conjugating enzyme E2 Z (EC 6.3.2.19) (Uba6-specific E2 conjugating enzyme 1) (Use1) (Ubiquitin carrier protein Z) (Ubiquitin-protein ligase Z)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9H832
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9H832/entry
Mouse Swissprot No.
Q3UE37
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q3UE37
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q3B7D1
免疫原
Synthesized peptide derived from part region of human protein
特异性
UBE2Z Polyclonal Antibody detects endogenous levels of protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes an enzyme which ubiquitinates proteins which participate in signaling pathways and apoptosis. [provided by RefSeq, Feb 2012],
组织表达
Widely expressed. Highly in placenta, pancreas, spleen and testis.
细胞定位
Cytoplasm . Nucleus .
信号通路
Ubiquitin mediated proteolysis;
功能
catalytic activity:ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.,function:Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity). Specific substrate for UBE1L2, not charged with ubiquitin by UBE1. May be involved in apoptosis regulation.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the ubiquitin-conjugating enzyme family.,tissue specificity:Widely expressed. Highly in placenta, pancreas, spleen and testis.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
