BD-PB4439-POLDIP3 Rabbit Polyclonal Antibody (N-term)-现货抗体产品库武汉枢密脑科学技术有限公司

POLDIP3 Rabbit Polyclonal Antibody (N-term)

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产品基本信息

产品货号

BD-PB4439

产品名称

POLDIP3 Rabbit Polyclonal Antibody (N-term)

别名

Polymerase delta-interacting protein 3, 46 kDa DNA polymerase delta interaction protein, p46, S6K1 Aly/REF-like target, SKAR, POLDIP3, KIAA1649, PDIP46

类别

常规抗体

推荐应用

反应种属

Human, Mouse

存储缓冲液

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) New type preservative N. This antibody is purified through a protein A column, followed by peptide affinity purification.

Human Gene ID

NP_115687.2;NP_835237.1

Human Swissprot No.

Q9BY77

特异性

This POLDIP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-120 amino acids from the N-terminal region of human POLDIP3.

稀释度

IF~~1:25;IHC-P~~1:100~500;WB~~1:1000

预测分子量

46kDa

运输及保存条件

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

宿主

Rabbit

同种型

Rabbit IgG

背景介绍

This gene encodes a protein that interacts with the DNA polymerase delta p50 subunit. This protein is a specific target of S6 kinase 1 and regulates cell growth. Two transcript variants that encode different protein isoforms have been identified. [provided by RefSeq].

细胞定位

Nucleus. Nucleus speckle. Cytoplasm. Note=Nucleocytoplasmic shuttling protein

功能

Is involved in regulation of translation. Is preferentially associated with CBC-bound spliced mRNA-protein complexes during the pioneer round of mRNA translation. Contributes to enhanced translational efficiency of spliced over nonspliced mRNAs. Recruits activated ribosomal protein S6 kinase beta-1 I/RPS6KB1 to newly synthesized mRNA. Involved in nuclear mRNA export; probably mediated by association with the TREX complex.

期货

现货

Fluorescent image of Hela cells stained with POLDIP3 Antibody (N-term). BD-PB4439 was diluted at 1:25 dilution. An Alexa Fluor 488-conjugated goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody (green). Cytoplasmic actin was counterstained with Alexa Fluor® 555 conjugated with Phalloidin (red).

Immunohistochemical analysis of paraffin-embedded H. stomach section using POLDIP3 Antibody (N-term). BD-PB4439 was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.

POLDIP3 Antibody (N-term) western blot analysis in Jurkat,mouse C2C12 cell line lysates (35ug/lane).This demonstrates the POLDIP3 Antibody antibody detected the POLDIP3 Antibody protein (arrow).