产品名称
UBAP1 Rabbit Polyclonal Antibody
蛋白名称
Ubiquitin-associated protein 1 (UBAP-1) (Nasopharyngeal carcinoma-associated gene 20 protein)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9NZ09
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NZ09/entry
Mouse Swissprot No.
Q8BH48
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BH48
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q5XIS7
免疫原
Synthesized peptide derived from part region of human protein
特异性
UBAP1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is a member of the UBA domain family, whose members include proteins having connections to ubiquitin and the ubiquitination pathway. The ubiquitin associated domain is thought to be a non-covalent ubiquitin binding domain consisting of a compact three helix bundle. This particular protein originates from a gene locus in a refined region on chromosome 9 undergoing loss of heterozygosity in nasopharyngeal carcinoma (NPC). Taking into account its cytogenetic location, this UBA domain family member is being studies as a putative target for mutation in nasopharyngeal carcinomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010],
组织表达
Ubiquitous. Highly expressed in heart, brain, placenta, lung, liver, skeletal muscle and pancreas.
细胞定位
Cytoplasm, cytosol . Endosome . Predominantly cytosolic (PubMed:21757351). Recruited to endosomes as part of the ESCRT-I complex (PubMed:21757351). .
功能
similarity:Contains 2 UBA domains.,tissue specificity:Ubiquitous. Highly expressed in heart, brain, placenta, lung, liver, skeletal muscle and pancreas.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
