产品名称
HSF2 Rabbit Polyclonal Antibody (Center)
别名
Heat shock factor protein 2, HSF 2, Heat shock transcription factor 2, HSTF 2, HSF2, HSTF2
存储缓冲液
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) New type preservative N. This antibody is purified through a protein A column, followed by peptide affinity purification.
Human Gene ID
NP_001129036.1;NP_004497.1
Human Swissprot No.
Q03933
特异性
This HSF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 216-245 amino acids from the Central region of human HSF2.
运输及保存条件
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
背景介绍
HSF2, as well as the related gene HSF1, encodes a protein
that binds specifically to the heat-shock element and has homology
to HSFs of other species. Heat shock transcription factors activate
heat-shock response genes under conditions of heat or other
stresses. Although the names HSF1 and HSF2 were chosen for
historical reasons, these peptides should be referred to as
heat-shock transcription factors.
细胞定位
Cytoplasm. Nucleus. Note=Cytoplasmic during normal growth and moves to the nucleus upon activation
功能
DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.
