产品名称
RFX4 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/5992
Human Swissprot No.
Q33E94
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q33E94/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/71137
Mouse Swissprot No.
Q7TNK1
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q7TNK1
免疫原
Synthesized peptide derived from human RFX4 AA range: 439-489
特异性
This antibody detects endogenous levels of RFX4 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X3, and X5. It has been shown to interact with itself as well as with regulatory factors X2 and X3, but it does not interact with regulatory factor X1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011],
组织表达
Isoform 1: Expressed in brain and gliomas (at protein level). Isoform 2: Testis-specific (at protein level). Isoform 3: Testis-specific (at protein level). Isoform 3: Expressed at a higher level in adult testes and ejaculated spematozoa than in fetal testes. Isoform 4: Testis-specific.
功能
function:May activate transcription by interacting directly with the X-box.,similarity:Belongs to the RFX family.,subunit:Homodimer. Heterodimer with RFX2 and RFX3. Binds DNA.,tissue specificity:Isoform 4 is testis-specific. Isoform 1 is expressed in brain and gliomas. Isoform 2 and isoform 3 are testis-specific (at protein level). Isoform 1 is expressed in brain (at protein level). Isoform 3 is expressed at a higher level in adult testes and ejaculated spematozoa than in fetal testes.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
