产品名称
AATK Rabbit Polyclonal Antibody (N-term)
别名
Serine/threonine-protein kinase LMTK1, Apoptosis-associated tyrosine kinase, AATYK, Brain apoptosis-associated tyrosine kinase, CDK5-binding protein, Lemur tyrosine kinase 1, p35-binding protein, p35BP, AATK, AATYK, KIAA0641, LMR1, LMTK1
存储缓冲液
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) New type preservative N. This antibody is purified through a protein A column, followed by peptide affinity purification.
Human Gene ID
NP_001073864.2;NP_004911.2
Human Swissprot No.
Q6ZMQ8
特异性
This AATK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-74 amino acids from the N-terminal region of human AATK.
运输及保存条件
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
背景介绍
The protein encoded by this gene contains a tyrosine
kinase domain at the N-terminus and a proline-rich domain at the
C-terminus. This gene is induced during apoptosis, and expression
of this gene may be a necessary pre-requisite for the induction of
growth arrest and/or apoptosis of myeloid precursor cells. This
gene has been shown to produce neuronal differentiation in a
neuroblastoma cell line.
组织表达
Expressed in brain..
细胞定位
Membrane; Single-pass type I membrane protein. Cytoplasm. Cytoplasm, perinuclear region. Note=Predominantly perinuclear
功能
May be involved in neuronal differentiation.