产品名称
NR2F2 Rabbit Polyclonal Antibody (N-term)
别名
COUP transcription factor 2, COUP-TF2, Apolipoprotein A-I regulatory protein 1, ARP-1, COUP transcription factor II, COUP-TF II, Nuclear receptor subfamily 2 group F member 2, NR2F2, ARP1, TFCOUP2
存储缓冲液
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) New type preservative N. This antibody is purified through a protein A column, followed by peptide affinity purification.
Human Gene ID
NP_001138627.1;NP_001138628.1;NP_001138629.1;NP_066285.1
Human Swissprot No.
P24468
特异性
This NR2F2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human NR2F2.
运输及保存条件
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
背景介绍
This gene encodes a member of the steroid thyroid hormone
superfamily of nuclear receptors. The encoded protein is a ligand
inducible transcription factor that is involved in the regulation
of many different genes. Alternate splicing results in multiple
transcript variants.
组织表达
Ubiquitous. Expressed in the stromal cells of developing fetal ovaries (PubMed:29478779)
功能
Ligand-activated transcription factor. Activated by high concentrations of 9-cis-retinoic acid and all-trans-retinoic acid, but not by dexamethasone, cortisol or progesterone (in vitro). Regulation of the apolipoprotein A-I gene transcription. Binds to DNA site A. May be required to establish ovary identity during early gonad development (PubMed:
29478779).