产品名称
RPL34 Rabbit Polyclonal Antibody (Center)
别名
60S ribosomal protein L34, RPL34
存储缓冲液
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) New type preservative N. This antibody is purified through a protein A column, followed by peptide affinity purification.
Human Gene ID
NP_000986.2;NP_296374.1
Human Swissprot No.
P49207
特异性
This RPL34 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the Central region of human RPL34.
运输及保存条件
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
背景介绍
Ribosomes, the organelles that catalyze protein synthesis,
consist of a small 40S subunit and a large 60S subunit. Together
these subunits are composed of 4 RNA species and approximately 80
structurally distinct proteins. This gene encodes a ribosomal
protein that is a component of the 60S subunit. The protein belongs
to the L34E family of ribosomal proteins. It is located in the
cytoplasm. This gene originally was thought to be located at 17q21,
but it has been mapped to 4q. Transcript variants derived from
alternative splicing, alternative transcription initiation sites,
and/or alternative polyadenylation exist; these variants encode the
same protein. As is typical for genes encoding ribosomal proteins,
there are multiple processed pseudogenes of this gene dispersed
through the genome.
细胞定位
Cytoplasm, cytosol. Cytoplasm Endoplasmic reticulum {ECO:0000250|UniProtKB:Q29223}. Note=Detected on cytosolic polysomes (PubMed:25957688). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity) {ECO:0000250|UniProtKB:Q29223, ECO:0000269|PubMed:25957688}
功能
Component of the large ribosomal subunit.
