BD-PB4313-CCDC36 Rabbit Polyclonal Antibody (C-term)-现货抗体产品库武汉枢密脑科学技术有限公司

CCDC36 Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号

BD-PB4313

产品名称

CCDC36 Rabbit Polyclonal Antibody (C-term)

别名

Coiled-coil domain-containing protein 36, Cancer/testis antigen 74, CT74, CCDC36

类别

常规抗体

推荐应用

反应种属

Human

存储缓冲液

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) New type preservative N. This antibody is purified through a protein A column, followed by peptide affinity purification.

Human Gene ID

NP_001128669.1;NP_835467.2

Human Swissprot No.

Q8IYA8

特异性

This CCDC36 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 422-450 amino acids from the C-terminal region of human CCDC36.

稀释度

WB~~1:1000;IHC-P~~1:100~500;IF~~1:10~50

预测分子量

66kDa

运输及保存条件

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

宿主

Rabbit

同种型

Rabbit IgG

细胞定位

Chromosome {ECO:0000250|UniProtKB:Q6PDM4}. Note=Specifically localizes to unsynapsed chromosomal regions during meiosis. {ECO:0000250|UniProtKB:Q6PDM4}

功能

Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance.

期货

现货

Western blot analysis of lysates from 293,Neuro-2a cell line and mouse liver tissue (from left to right),using CCDC36 Antibody (C-term)at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug per lane.

CCDC36 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Confocal immunofluorescent analysis of CCDC36 Antibody (C-term)with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).