BD-PB4227

FKBP1A (12Z14) Mouse Monoclonal Antibody

Peptidyl-prolyl cis-trans isomerase FKBP1A, PPIase FKBP1A, 5.2.1.8, 12 kDa FK506-binding protein, 12 kDa FKBP, FKBP-12, Calstabin-1, FK506-binding protein 1A, FKBP-1A, Immunophilin FKBP12, Rotamase, FKBP1A, FKBP1, FKBP12

常规抗体

WB

Human, Rat, Mouse

P62942

This antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between amino acids from human.

WB~~1:4000

12kDa

IgG1,κ

Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruits SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

Cytoplasm, cytosol. Sarcoplasmic reticulum membrane {ECO:0000250|UniProtKB:P62943}; Peripheral membrane protein {ECO:0000250|UniProtKB:P62943}; Cytoplasmic side {ECO:0000250|UniProtKB:P62943}

现货