BD-PB4219

PURB (9I19) Mouse Monoclonal Antibody (C-term)

Transcriptional activator protein Pur-beta, Purine-rich element-binding protein B, PURB

常规抗体

WB

Human, Mouse

Q96QR8

This PURB antibody is generated from a mouse immunized with a recombiant protein of human PURB.

WB~~1:8000

33kDa

IgG1,κ

Has capacity to bind repeated elements in single- stranded DNA such as the purine-rich single strand of the PUR element located upstream of the MYC gene. Plays a role in the control of vascular smooth muscle (VSM) alpha-actin gene transcription as repressor in myoblasts and fibroblasts. Participates in transcriptional and translational regulation of alpha-MHC expression in cardiac myocytes by binding to the purine- rich negative regulatory (PNR) element. Modulates constitutive liver galectin-3 gene transcription by binding to its promoter. May play a role in the dendritic transport of a subset of mRNAs (By similarity).

Expressed in myocardium of heart failure patients.

Nucleus.

现货