BD-PB4201-PDCD1LG2 (13V12) Mouse Monoclonal Antibody (N-term)-现货抗体产品库武汉枢密脑科学技术有限公司

PDCD1LG2 (13V12) Mouse Monoclonal Antibody (N-term)

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产品基本信息

产品货号

BD-PB4201

产品名称

PDCD1LG2 (13V12) Mouse Monoclonal Antibody (N-term)

别名

Programmed cell death 1 ligand 2, PD-1 ligand 2, PD-L2, PDCD1 ligand 2, Programmed death ligand 2, Butyrophilin B7-DC, B7-DC, CD273, PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2

类别

常规抗体

推荐应用

反应种属

Human

Human Swissprot No.

Q9BQ51

特异性

This PDCD1LG2 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 40-75 amino acids from the N-terminal region of human PDCD1LG2.

稀释度

IHC-P~~1:100~500;WB~~1:8000

预测分子量

31kDa

同种型

IgG1,κ

背景介绍

Involved in the costimulatory signal, essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity).

组织表达

Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus

细胞定位

[Isoform 3]: Secreted [Isoform 1]: Cell membrane; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q9WUL5, ECO:0000305|PubMed:15340161}

期货

现货

Immunohistochemical analysis of PDL-2 in untransfected(left) or transfected(right) with 293T cell sections. Cell was fixed with formaldehyde; antigen retrieval was by heat mediation with a EDTA buffer (pH9. 0). Samples were incubated with primary antibody (1:25) for 1 hours at room temperature. A undiluted biotinylated goat polyvalent antibody was used as the secondary antibody.

All lanes : Anti-PDCD1LG2 Antibody (N-term) at 1:8000 dilution Lane 1: Non-transfected 293T whole cell lysate Lane 2: Transfected PD-L2-transfected 293T whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 31 kDa Blocking/Dilution buffer: 5% NFDM/TBST.