BD-PB4194

FOLR2 (3G9) Mouse Monoclonal Antibody

Folate receptor beta, FR-beta, Folate receptor 2, Folate receptor, fetal/placental, Placental folate-binding protein, FBP, FOLR2

常规抗体

WB

Human, Mouse

P14207

This FOLR2 antibody is generated from a mouse immunized with a recombiant protein from human FOLR2.

WB~~1:1000-1:2000

29kDa

IgG2b,κ

Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release.

Expressed in placenta and hematopoietic cells. Expression is increased in malignant tissues

Cell membrane; Lipid-anchor, GPI-anchor. Secreted

现货