BD-PB4155

RAB20 (6Z5) Mouse Monoclonal Antibody

Ras-related protein Rab-20, RAB20

常规抗体

WB

Human, Mouse

Q9NX57

This RAB20 antibody is generated from a mouse immunized with recombinant protein from human RAB20.

WB~~1:2000-1:4000

26kDa

IgG2a

Plays a role in apical endocytosis/recycling. Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes.

Low or absent expression in normal pancreas and stronger expression in 15 of 18 exocrine pancreatic adenocarcinomas (at protein level).

Golgi apparatus. Cytoplasmic vesicle, phagosome Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Note=Highly enriched on apical endocytic structures in polarized epithelial cells of kidney proximal tubules (By similarity). Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211) {ECO:0000250|UniProtKB:P35295, ECO:0000269|PubMed:21255211}

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