BD-PB4132

LAP2 (14S7) Mouse Monoclonal Antibody

Protein LAP2, Densin-180-like protein, Erbb2-interacting protein, Erbin, ERBB2IP, ERBIN, KIAA1225, LAP2

常规抗体

WB

Human, Rat, Mouse

Q96RT1

This LAP2 antibody is generated from a mouse immunized with a recombinant protein of human LAP2.

WB~~1:1000

158kDa

IgG1,k

Acts as an adapter for the receptor ERBB2, in epithelia. By binding the unphosphorylated 'Tyr-1248' of receptor ERBB2, it may contribute to stabilize this unphosphorylated state.

Highly expressed in brain, heart, kidney, muscle and stomach, followed by liver, spleen and intestine

Cell junction, hemidesmosome. Nucleus membrane. Basolateral cell membrane. Note=Found in hemidesmosomes, which are cell-substrate adhesion complexes in stratified epithelia. In transfected cells, either diffusely distributed over the cytoplasm or concentrated at the basolateral membrane. Colocalizes with the adrenergic receptors, ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes (By similarity).

现货