BD-PB4110-BAP31 (12E15) Mouse Monoclonal Antibody-现货抗体产品库武汉枢密脑科学技术有限公司

BAP31 (12E15) Mouse Monoclonal Antibody

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产品基本信息

产品货号

BD-PB4110

产品名称

BAP31 (12E15) Mouse Monoclonal Antibody

别名

B-cell receptor-associated protein 31, BCR-associated protein 31, Bap31, 6C6-AG tumor-associated antigen, Protein CDM, p28, BCAP31, BAP31, DXS1357E

类别

常规抗体

推荐应用

反应种属

Human, Mouse

Human Swissprot No.

P51572

特异性

This BAP31 antibody is generated from a mouse immunized with a recombinant.

稀释度

IHC-P~~1:100~500;WB~~1:2000

预测分子量

28kDa

同种型

IgG1,k

背景介绍

Functions as a chaperone protein. Is one of the most abundant endoplasmic reticulum (ER) proteins. Plays a role in the export of secreted proteins in the ER, the recognition of abnormally folded protein and their targeting to the ER associated-degradation (ERAD). Also serves as a cargo receptor for the export of transmembrane proteins. May be involved in CASP8- mediated apoptosis.

组织表达

Ubiquitous. Highly expressed in neurons and discrete endocrine cells.

细胞定位

Endoplasmic reticulum membrane; Multi-pass membrane protein Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Note=May shuttle between the ER and the intermediate compartment/cis-Golgi complex (PubMed:9396746). Associates with the mitochondria-associated endoplasmic reticulum membrane via interaction with TOMM40 (PubMed:31206022)

期货

现货

BD-PB4110 staining BAP31 in human brain sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed with formaldehyde and blocked with 3% BSA for 0. 5 hour at room temperature; antigen retrieval was by heat mediation with a citrate buffer (pH6). Samples were incubated with primary antibody (1/25) for 1 hours at 37°C. A undiluted biotinylated goat polyvalent antibody was used as the secondary antibody.

All lanes : Anti-BAP31 Antibody at 1:2000 dilution Lane 1: A431 whole cell lysates Lane 2: NCCIT whole cell lysates Lysates/proteins at 20 μg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 28 kDa Blocking/Dilution buffer: 5% NFDM/TBST.