产品名称
TNNC2 Rabbit Polyclonal Antibody
蛋白名称
Troponin C, skeletal muscle
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P02585
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P02585/entry
Mouse Swissprot No.
P20801
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P20801
免疫原
Synthesized peptide derived from part region of human protein
特异性
TNNC2 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit. [provided by RefSeq, Jul 2008],
组织表达
Liver,Muscle,Skeletal muscle,Tongue,
细胞定位
cytosol,troponin complex,
功能
function:Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.,miscellaneous:Skeletal muscle troponin C binds four calcium ions.,similarity:Belongs to the troponin C family.,similarity:Contains 4 EF-hand domains.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
