BD-PB4080

PPARA (7B3) Mouse Monoclonal Antibody

Peroxisome proliferator-activated receptor alpha, PPAR-alpha, Nuclear receptor subfamily 1 group C member 1, PPARA, NR1C1, PPAR

常规抗体

WB

Human, Mouse

Q07869

This PPARA antibody is generated from a mouse immunized with a recombination protein from the human region of human PPARA.

WB~~1:1000

52kDa

IgG1,κ

Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl- 2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety (By similarity). Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2.

Skeletal muscle, liver, heart and kidney. Expressed in monocytes (PubMed:28167758).

Nucleus.

现货