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BCL10 (9A9) Mouse Monoclonal Antibody

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产品基本信息

产品货号
BD-PB4074
产品名称
BCL10 (9A9) Mouse Monoclonal Antibody
别名
B-cell lymphoma/leukemia 10, B-cell CLL/lymphoma 10, Bcl-10, CARD-containing molecule enhancing NF-kappa-B, CARD-like apoptotic protein, hCLAP, CED-3/ICH-1 prodomain homologous E10-like regulator, CIPER, Cellular homolog of vCARMEN, cCARMEN, Cellular-E10, c-E10, Mammalian CARD-containing adapter molecule E10, mE10, BCL10, CIPER, CLAP
类别
常规抗体
推荐应用
WB
反应种属
Human
Human Swissprot No.
O95999
特异性
This BCL10 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 1-143 amino acids from the human region of human BCL10.
稀释度
FC~~1:25;IHC-P~~1:100~500;WB~~1:2000
预测分子量
26kDa
同种型
IgG1,κ
背景介绍
Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1.
组织表达
Ubiquitous..
细胞定位
Cytoplasm, perinuclear region. Membrane raft. Note=Appears to have a perinuclear, compact and filamentous pattern of expression. Also found in the nucleus of several types of tumor cells. Colocalized with DPP4 in membrane rafts.
期货
现货

Flow cytometric analysis of Hela cells using BCL10 Antibody(green) compared to an isotype control of mouse IgG1(blue). BD-PB4074 was diluted at 1:25 dilution. An Alexa Fluor® 488 goat anti-mouse lgG at 1:400 dilution was used as the secondary antibody.

Immunohistochemical analysis of paraffin-embedded H. kidney section using BCL10 Antibody. BD-PB4074 was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-mouse IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.

Immunohistochemical analysis of paraffin-embedded M. kidney section using BCL10 Antibody. BD-PB4074 was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-mouse IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.

Western blot analysis of lysate from Daudi cell line using BCL10 Antibody at 1:3000 dilution was used as the secondary antibody. Lysate at 35μg per lane.

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