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USP25 (3A12) Mouse Monoclonal Antibody

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产品基本信息

产品货号
BD-PB4069
产品名称
USP25 (3A12) Mouse Monoclonal Antibody
别名
Ubiquitin carboxyl-terminal hydrolase 25, Deubiquitinating enzyme 25, USP on chromosome 21, Ubiquitin thioesterase 25, Ubiquitin-specific-processing protease 25, USP25, USP21
类别
常规抗体
推荐应用
WB
反应种属
Human
Human Swissprot No.
Q9UHP3
特异性
This USP25 antibody is generated from a mouse immunized with a recombinant protein from human USP25.
稀释度
WB~~1:1000
预测分子量
122kDa
同种型
IgG1,κ
背景介绍
Deubiquitinating enzyme that hydrolyzes ubiquitin moieties conjugated to substrates and thus, functions to process newly synthesized Ubiquitin, to recycle ubiquitin molecules or to edit polyubiquitin chains and prevents proteasomal degradation of substrates. Hydrolyzes both 'Lys-48'- and 'Lys-63'-linked tetraubiquitin chains.
组织表达
Isoform USP25a is found in most adult and fetal tissues; expression is moderately high in testis, pancreas, kidney, skeletal muscle, liver, lung, placenta, brain, heart, but very low in peripheral blood, colon, small intestine, ovary, prostate, thymus and spleen. Isoform USP25b is found in all tissues except heart and skeletal muscle. Isoform USP25m is heart and skeletal muscle specific
细胞定位
Cytoplasm
期货
现货

Western blot analysis of lysate from Daudi cell line, using USP25 Antibody at 1:5000 dilution was used as the secondary antibody. Lysate at 35μg.

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