BD-PB4067

POU2AF1 (7B12) Mouse Monoclonal Antibody

POU domain class 2-associating factor 1, B-cell-specific coactivator OBF-1, BOB-1, OCA-B, OCT-binding factor 1, POU2AF1, OBF1

常规抗体

WB

Human

NP_006226.2

Q16633

Purified His-tagged POU2AF1 protein was used to produced this monoclonal antibody.

WB~~1:4000

27kDa

IgG1,κ

Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers.

B-cell specific (PubMed:7779176, PubMed:7859290). Detected in mainly in spleen, but also in thymus, periphral blood leukocyte and small intestine (PubMed:7779176, PubMed:7859290)

Nucleus.

现货