产品名称
SEC62 Rabbit Polyclonal Antibody
蛋白名称
Translocation protein SEC62 (Translocation protein 1) (TP-1) (hTP-1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q99442
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q99442/entry
Mouse Swissprot No.
Q8BU14
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BU14
免疫原
Synthesized peptide derived from part region of human protein
特异性
SEC62 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008],
组织表达
Epithelium,Liver,Mammary gland,Prostate,
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
功能
function:Required for preprotein translocation.,similarity:Belongs to the SEC62 family.,subunit:Part of a complex that contains SEC61, SEC62 and SEC63. Interacts with SEC61B.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
