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HS2ST1 Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号
BD-PB4022
产品名称
HS2ST1 Rabbit Polyclonal Antibody (Center)
别名
Heparan sulfate 2-O-sulfotransferase 1, 2-O-sulfotransferase, 2OST, 282-, HS2ST1, HS2ST, KIAA0448
类别
常规抗体
推荐应用
WB
反应种属
Human
Human Gene ID
NP_001127964.1;NP_036394.1
Human Swissprot No.
Q7LGA3
特异性
This HS2ST1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-200 amino acids from the Central region of human HS2ST1.
稀释度
WB~~1:1000;IHC-P~~1:100~500
预测分子量
42kDa
同种型
Rabbit IgG
背景介绍
Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. This gene encodes heparan sulfate 2-O-sulfotransferase, a member of the heparan sulfate biosynthetic enzyme family. This family member transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of this gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation.
细胞定位
Golgi apparatus membrane; Single- pass type II membrane protein
期货
现货

Western blot analysis of anti-HS2ST1 Antibody (Center) Pab in Ramos and CEM cell line lysates. HS2ST1(arrow) was detected using the purified Pab.

Western blot analysis of anti-HS2ST1 Antibody (Center) Pab in 293 cell line lysates transiently transfected with the HS2ST1 gene (2ug/lane). HS2ST1(arrow) was detected using the purified Pab.

Western blot analysis of anti-HS2ST1 Antibody (Center) Pab in 293 cell line lysates transiently transfected with the HS2ST1 gene (2ug/lane). HS2ST1 Antibody (Center)(arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded human brain tissue reacted with HS2ST1 antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

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