BD-PB4018-EIF4A1 Rabbit Polyclonal Antibody (N-term)-现货抗体产品库武汉枢密脑科学技术有限公司

EIF4A1 Rabbit Polyclonal Antibody (N-term)

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产品基本信息

产品货号

BD-PB4018

产品名称

EIF4A1 Rabbit Polyclonal Antibody (N-term)

别名

Eukaryotic initiation factor 4A-I, eIF-4A-I, eIF4A-I, ATP-dependent RNA helicase eIF4A-1, EIF4A1, DDX2A, EIF4A

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_001191439.1;NP_001407.1

Human Swissprot No.

P60842

特异性

This EIF4A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human EIF4A1.

稀释度

WB~~1:1000;IHC-P~~1:100~500

预测分子量

46kDa

同种型

Rabbit IgG

背景介绍

EIF4A1 is an ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

期货

现货

Western blot analysis of anti-EIF4A1 Pab in K562 cell line lysates (35ug/lane). EIF4A1(arrow) was detected using the purified Pab.

Western blot analysis of EIF4A1 (arrow) using rabbit polyclonal EIF4A1 Antibody (N-term) either nontransfected (Lane 1) or transiently transfected with the EIF4A1 gene (Lane 2) .

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with EIF4A1 antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.