BD-PB4012-MVD Rabbit Polyclonal Antibody (Center)-现货抗体产品库武汉枢密脑科学技术有限公司

MVD Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号

BD-PB4012

产品名称

MVD Rabbit Polyclonal Antibody (Center)

别名

Diphosphomevalonate decarboxylase, Mevalonate (diphospho)decarboxylase, MDDase, Mevalonate pyrophosphate decarboxylase, MVD, MPD

类别

常规抗体

推荐应用

反应种属

Human, Rat, Mouse

Human Gene ID

NP_002452.1

Human Swissprot No.

P53602

特异性

This MVD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-193 amino acids from the Central region of human MVD.

稀释度

WB~~1:1000;IHC-P~~1:100~500;FC~~1:10~50

预测分子量

43kDa

同种型

Rabbit IgG

背景介绍

The enzyme mevalonate pyrophosphate decarboxylase catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate in one of the early steps in cholesterol biosynthesis. It decarboxylates and dehydrates its substrate while hydrolyzing ATP.

组织表达

Expressed in heart, skeletal muscle, lung, liver, brain, pancreas, kidney and placenta.

细胞定位

Cytoplasm.

期货

现货

All lanes : Anti-MVD Antibody (Center) at 1:1000 dilution Lane 1: HL-60 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/15000 dilution. Observed band size : 43kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Western blot analysis of MVD Antibody (Center)in HL60 cell line lysates (35ug/lane). MVD (arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded human Skeletal muscle reacted with MVD Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

MVD Antibody (Center) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.