BD-PB4011

PRELP Rabbit Polyclonal Antibody (Center)

Prolargin, Proline-arginine-rich end leucine-rich repeat protein, PRELP, SLRR2A

常规抗体

WB

Human, Rat, Mouse

NP_002716.1;NP_958505.1

P51888

This PRELP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-148 amino acids from the Central region of human PRELP.

WB~~1:1000

44kDa

Rabbit IgG

PRELP is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage.

Connective tissue.

Secreted, extracellular space, extracellular matrix

现货