BD-PB4005-FXN Rabbit Polyclonal Antibody (C-term)-现货抗体产品库武汉枢密脑科学技术有限公司

FXN Rabbit Polyclonal Antibody (C-term)

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产品基本信息

产品货号

BD-PB4005

产品名称

FXN Rabbit Polyclonal Antibody (C-term)

别名

Frataxin, mitochondrial, Friedreich ataxia protein, Fxn, Frataxin intermediate form, i-FXN, Frataxin(56-210), m56-FXN, Frataxin(78-210), d-FXN, m78-FXN, Frataxin mature form, Frataxin(81-210), m81-FXN, FXN, FRDA, X25

类别

常规抗体

推荐应用

反应种属

Human

Human Gene ID

NP_000135.2;NP_001155178.1;NP_852090.1

Human Swissprot No.

Q16595

特异性

This FXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-172 amino acids from the C-terminal region of human FXN.

稀释度

WB~~1:1000;IHC-P~~1:100~500

预测分子量

23kDa

同种型

Rabbit IgG

背景介绍

FXN is a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia.

组织表达

Expressed in the heart, peripheral blood lymphocytes and dermal fibroblasts.

细胞定位

Mitochondrion. Cytoplasm, cytosol. Note=PubMed:18725397 reports localization exclusively in mitochondria.

期货

现货

Western blot analysis of anti-FXN Antibody (C-term) in 293 cell line lysates (35ug/lane). FXN (arrow) was detected using the purified Pab.

Western blot analysis of FXN (arrow) using rabbit polyclonal FXN Antibody (C-term) either nontransfected (Lane 1) or transiently transfected with the FXN gene (Lane 2) .

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with FXN antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.