BD-PB3960

CDH10 Rabbit Polyclonal Antibody (N-term)

Cadherin-10, T2-cadherin, CDH10

常规抗体

WB

Human

NP_006718.2

Q9Y6N8

This CDH10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-55 amino acids from the N-terminal region of human CDH10.

WB~~1:1000;IHC-P~~1:100~500;FC~~1:10~50

88kDa

Rabbit IgG

CDH10 is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is predominantly expressed in brain and is putatively involved in synaptic adhesions, axon outgrowth and guidance.

Predominantly expressed in brain. Also found in adult and fetal kidney. Very low levels detected in prostate and fetal lung.

Cell membrane; Single-pass type I membrane protein

现货