BD-PB3956

TMPRSS13 Rabbit Polyclonal Antibody (C-term)

Transmembrane protease serine 13, 3421-, Membrane-type mosaic serine protease, Mosaic serine protease, TMPRSS13, MSP, TMPRSS11

常规抗体

WB

Human

NP_001193719.1;NP_001231924.1

Q9BYE2

This TMPRSS13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 431-460 amino acids from the C-terminal region of human TMPRSS13.

WB~~1:1000;IHC-P~~1:100~500

63kDa

Rabbit IgG

TMPRSS13 is a cell membrane serine protease. It is a member of a larger family of membrane attached serine proteases, a poorly defined group that includes TMPRSS11A, B, C, D, E, F, Hepsin, Corin, Matriptase 1, 2 and 3. TMPRSS13 has a domain structure of an aminoterminal cytoplasmic domain, which is much longer than the other TMPRSS family members, followed by a transmembrane domain, an SRCR domain (Scavenger receptor cysteine rich), an LDL receptor like domain, another SRCR domain, followed by the trypsin like serine protease domain. The cytoplasmic domain contains a number of tandem repeat elements, the function of which is not clear, but which may play a regulatory role.

Isoform 1 and isoform 3 are predominantly expressed in lung, placenta, pancreas, and prostate. Isoform 3 is weakly expressed in testis and peripheral blood lymphocytes

Membrane; Single-pass type II membrane protein

现货