BD-PB3936

ULK3 Rabbit Polyclonal Antibody (C-term)

Serine/threonine-protein kinase ULK3, Unc-51-like kinase 3, ULK3

常规抗体

WB

Mouse

NP_001092906.1

Q6PHR2

This ULK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 347-375 amino acids from the C-terminal region of human ULK3.

WB~~1:1000

53kDa

Rabbit IgG

Serine/threonine protein kinase which enhances GLI1 and GLI2 transcriptional activity and consequently positively regulates GLI-dependent SHH signaling. May exert this function by promoting GLI1 nuclear localization. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently.

Widely expressed. Highest levels observed in fetal brain. In adult tissues, high levels in brain, liver and kidney, moderate levels in testis and adrenal gland and low levels in heart, lung, stomach, thymus, prostate and placenta. In the brain, highest expression in the hippocampus, high levels also detected in the cerebellum, olfactory bulb and optic nerve. In the central nervous system, lowest levels in the spinal cord

Cytoplasm. Note=Localizes to pre-autophagosomal structure during cellular senescence

现货