BD-PB3934-NHLRC1 Rabbit Polyclonal Antibody (Center)-现货抗体产品库武汉枢密脑科学技术有限公司

NHLRC1 Rabbit Polyclonal Antibody (Center)

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产品基本信息

产品货号

BD-PB3934

产品名称

NHLRC1 Rabbit Polyclonal Antibody (Center)

别名

E3 ubiquitin-protein ligase NHLRC1, 632-, Malin, NHL repeat-containing protein 1, NHLRC1, EPM2B

类别

常规抗体

推荐应用

反应种属

Human, Rat, Mouse

Human Gene ID

NP_940988.2

Human Swissprot No.

Q6VVB1

特异性

This NHLRC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-179 amino acids from the Central region of human NHLRC1.

稀释度

WB~~1:500-1:1000

预测分子量

42kDa

同种型

Rabbit IgG

背景介绍

The protein encoded by this gene is a single subunit E3 ubiquitin ligase. Laforin is polyubiquitinated by the encoded protein. Defects in this intronless gene lead to an accumulation of laforin and onset of Lafora disease, also known as progressive myoclonic epilepsy type 2 (EPM2).

组织表达

Expressed in brain, cerebellum, spinal cord, medulla, heart, liver, skeletal muscle and pancreas

细胞定位

Endoplasmic reticulum. Nucleus. Note=Localizes at the endoplasmic reticulum and, to a lesser extent, in the nucleus

期货

现货

All lanes : Anti-NHLRC1 Antibody (Center) at 1:500 dilution Lane 1: mouse heart lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/15000 dilution. Observed band size : 42kDa Blocking/Dilution buffer: 5% NFDM/TBST.