产品名称
JUP (9R3) Mouse Monoclonal Antibody (Ascites)
别名
Junction plakoglobin, Catenin gamma, Desmoplakin III, Desmoplakin-3, JUP, CTNNG, DP3
Human Gene ID
NP_002221.1;NP_068831.1
Human Swissprot No.
P14923
特异性
This JUP antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 636-663 amino acids from human JUP .
背景介绍
This gene encodes a major cytoplasmic protein which is the
only known constituent common to submembranous plaques of both
desmosomes and intermediate junctions. This protein forms distinct
complexes with cadherins and desmosomal cadherins and is a member
of the catenin family since it contains a distinct repeating amino
acid motif called the armadillo repeat. Mutation in this gene has
been associated with Naxos disease. Alternative splicing occurs in
this gene; however, not all transcripts have been fully described.
细胞定位
Cell junction, adherens junction. Cell junction, desmosome. Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein Note=Cytoplasmic in a soluble and membrane-associated form