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HNF1A (13S5) Mouse Monoclonal Antibody (Ascites)

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产品基本信息

产品货号
BD-PB3880
产品名称
HNF1A (13S5) Mouse Monoclonal Antibody (Ascites)
别名
Hepatocyte nuclear factor 1-alpha, HNF-1-alpha, HNF-1A, Liver-specific transcription factor LF-B1, LFB1, Transcription factor 1, TCF-1, HNF1A, TCF1
类别
常规抗体
推荐应用
WB
反应种属
Human
Human Gene ID
NP_000536.5
Human Swissprot No.
P20823
特异性
This HNF1A antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 177-205 amino acids from human HNF1A .
稀释度
WB~~1:100~1600
预测分子量
67kDa
同种型
IgG1
背景介绍
The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas.
组织表达
Liver.
细胞定位
Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:10966642}
期货
现货

HNF1A Antibody (Ascites)western blot analysis in NCI-H460 cell line lysates (35μg/lane).This demonstrates the HNF1A antibody detected the HNF1A protein (arrow).

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