产品名称
VTN (14B5) Mouse Monoclonal Antibody
别名
Vitronectin, VN, S-protein, Serum-spreading factor, V75, Vitronectin V65 subunit, Vitronectin V10 subunit, Somatomedin-B, VTN
Human Gene ID
NP_000629.3
Human Swissprot No.
P04004
特异性
This VTN antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 352-379 amino acids from human VTN.
背景介绍
The protein encoded by this gene is a member of the pexin
family. It is found in serum and tissues and promotes cell adhesion
and spreading, inhibits the membrane-damaging effect of the
terminal cytolytic complement pathway, and binds to several serpin
serine protease inhibitors. It is a secreted protein and exists in
either a single chain form or a clipped, two chain form held
together by a disulfide bond.
组织表达
Expressed in the retina pigment epithelium (at protein level) (PubMed:25136834). Expressed in plasma (at protein level) (PubMed:2448300). Expressed in serum (at protein level) (PubMed:29567995).
细胞定位
Secreted, extracellular space
