产品名称
COE3 Rabbit Polyclonal Antibody
蛋白名称
Transcription factor COE3 (Early B-cell factor 3) (EBF-3) (Olf-1/EBF-like 2) (O/E-2) (OE-2)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9H4W6
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9H4W6/entry
Mouse Swissprot No.
O08791
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O08791
免疫原
Synthesized peptide derived from human protein . at AA range: 50-130
特异性
COE3 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the early B-cell factor (EBF) family of DNA binding transcription factors. EBF proteins are involved in B-cell differentiation, bone development and neurogenesis, and may also function as tumor suppressors. The encoded protein inhibits cell survival through the regulation of genes involved in cell cycle arrest and apoptosis, and aberrant methylation or deletion of this gene may play a role in multiple malignancies including glioblastoma multiforme and gastric carcinoma. [provided by RefSeq, Sep 2011],
功能
function:Transcriptional activator which recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'.,similarity:Belongs to the COE family.,similarity:Contains 1 IPT/TIG domain.,subunit:Forms either a homodimer or a heterodimer with a related family member.,tissue specificity:Expressed in brain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
