BD-PB3871

HMG2 (11G4) Mouse Monoclonal Antibody (Ascites)

High mobility group protein HMGI-C, High mobility group AT-hook protein 2, HMGA2, HMGIC

常规抗体

WB

Human

NP_003474.1;NP_003475.1

P52926

This HMG2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from human HMG2.

WB~~1:500~8000

12kDa

IgG2b

This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Nucleus.

现货