产品名称
MX1 (1L9) Mouse Monoclonal Antibody (Ascites)
别名
Interferon-induced GTP-binding protein Mx1, Interferon-induced protein p78, IFI-78K, Interferon-regulated resistance GTP-binding protein MxA, Myxoma resistance protein 1, Myxovirus resistance protein 1, Interferon-induced GTP-binding protein Mx1, N-terminally processed, MX1
Human Gene ID
NP_001138397.1;NP_001171517.1;NP_002453.2
Human Swissprot No.
P20591
特异性
This MX1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 617-646 amino acids from human MX1.
背景介绍
In mouse, the interferon-inducible Mx protein is
responsible for a specific antiviral state against influenza virus
infection. The protein encoded by this gene is similar to the mouse
protein as determined by its antigenic relatedness, induction
conditions, physicochemical properties, and amino acid analysis.
This cytoplasmic protein is a member of both the dynamin family and
the family of large GTPases. Two transcript variants encoding the
same protein have been found for this gene.
细胞定位
Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, perinuclear region. Note=Binds preferentially to negatively charged phospholipids (PubMed:21900240). Colocalizes with CCHFV protein N in the perinuclear region (PubMed:15047845)
