BD-PB3862

DYRK2 (16J6) Mouse Monoclonal Antibody

Dual specificity tyrosine-phosphorylation-regulated kinase 2, DYRK2

常规抗体

WB

Human

NP_003574.1;NP_006473.2

Q92630

This DYRK2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 105-135 amino acids from human DYRK2.

WB~~1:500~1000

67kDa

IgG1

DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. Two isoforms of DYRK2 have been isolated. The predominant isoform, isoform 1, lacks a 5' terminal insert.

Testis, after the onset of spermatogenesis.

Cytoplasm. Nucleus. Note=Translocates into the nucleus following DNA damage

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