产品名称
BTF3 Rabbit Polyclonal Antibody
基因名称
BTF3 NACB OK/SW-cl.8
蛋白名称
Transcription factor BTF3 (RNA polymerase B transcription factor 3)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
P20290
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P20290/entry
Mouse Swissprot No.
Q64152
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q64152
免疫原
Synthesized peptide derived from human protein . at AA range: 120-200
特异性
BTF3 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes the basic transcription factor 3. This protein forms a stable complex with RNA polymerase IIB and is required for transcriptional initiation. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene has multiple pseudogenes. [provided by RefSeq, Jul 2008],
组织表达
Colon adenocarcinoma,Leukocyte,Skin,
细胞定位
Cytoplasm . Nucleus . The heterodimer with NACA is cytoplasmic.
功能
function:General transcription factor. BTF3 can form a stable complex with RNA polymerase II. Required for the initiation of transcription.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the NAC-beta family.,similarity:Contains 1 NAC-A/B (NAC-alpha/beta) domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
