产品名称
UBR3 Rabbit Polyclonal Antibody
基因名称
UBR3 KIAA2024 ZNF650
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/130507
Human Swissprot No.
Q6ZT12
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q6ZT12/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/68795
Mouse Swissprot No.
Q5U430
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q5U430
免疫原
Synthesized peptide derived from human UBR3 AA range: 1591-1641
特异性
This antibody detects endogenous levels of UBR3 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
细胞定位
Membrane ; Multi-pass membrane protein .
功能
function:E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Does not bind to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.,pathway:Protein modification; protein ubiquitination.,sequence caution:Translated as Gln.,similarity:Belongs to the UBR1 family.,similarity:Contains 1 RING-type zinc finger.,similarity:Contains 1 UBR-type zinc finger.,subunit:Interacts with UBE2A and UBE2B.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
