产品名称
STK39 (6B19) Mouse Monoclonal Antibody
别名
STE20/SPS1-related proline-alanine-rich protein kinase, Ste-20-related kinase, DCHT, Serine/threonine-protein kinase 39, STK39, SPAK
Human Gene ID
NP_037365.2
Human Swissprot No.
Q9UEW8
特异性
Purified His-tagged STK39 protein(Fragment) was used to produced this monoclonal antibody.
背景介绍
This gene encodes a serine/threonine kinase that is
thought to function in the cellular stress response pathway. The
kinase is activated in response to hypotonic stress, leading to
phosphorylation of several cation-chloride-coupled cotransporters.
The catalytically active kinase specifically activates the p38 MAP
kinase pathway, and its interaction with p38 decreases upon
cellular stress, suggesting that this kinase may serve as an
intermediate in the response to cellular stress. [provided by
RefSeq].
组织表达
Predominantly expressed in brain and pancreas followed by heart, lung, kidney, skeletal muscle, liver, placenta and testis
细胞定位
Cytoplasm. Nucleus. Note=Nucleus when caspase-cleaved.