产品名称
TCF25 Rabbit Polyclonal Antibody
基因名称
TCF25 KIAA1049 NULP1 FKSG26
蛋白名称
Transcription factor 25 (TCF-25) (Nuclear localized protein 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9BQ70
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9BQ70/entry
Mouse Swissprot No.
Q8R3L2
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8R3L2
免疫原
Synthesized peptide derived from part region of human protein
特异性
TCF25 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
TCF25 is a member of the basic helix-loop-helix (bHLH) family of transcription factors that are important in embryonic development (Steen and Lindholm, 2008 [PubMed 18068114]).[supplied by OMIM, Sep 2008],
组织表达
In the embryo, widely expressed with highest levels in brain. In the adult, highest expression is found in the heart.
细胞定位
Nucleus . Some staining in the cytosol.
功能
domain:The C-terminal region mediates transcriptional repression.,function:May play a role in cell death control. Acts as a transcriptional repressor. Has been shown to repress transcription of SRF in vitro and so may play a role in heart development.,similarity:Belongs to the TCF25 family.,subcellular location:Some staining in the cytosol.,subunit:Interacts with XIAP.,tissue specificity:In the embryo, widely expressed with highest levels in brain. In the adult, highest expression is found in the heart.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
